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BIOGRAPHICAL SKETCH

Provide the following information for the key personnel in the order listed on Form Page 2.

Photocopy this page or follow this format for each person.

  

NAME

 

Guido K.W. Frank

POSITION TITLE

 

Research Fellow

EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)

INSTITUTION AND LOCATION

DEGREE

(If applicable)

YEAR(s)

FIELD OF STUDY

Ludwig-Maximilians-Universitaet Munich, Germany

Psychosomatic Hospital Roseneck, Prien, Germany (Ludwig-Maximilians-University Munich, Germany)

Psychosomatic Hospital Roseneck, Prien, Germany (Ludwig-Maximilians-University Munich, Germany)

Center for Overcoming Problem Eating, Western Psychiatric Institute and Clinic, Pittsburgh, PA

Residency Training Program, Western Psychiatric

Institute and Clinic, Pittsburgh, PA

Residency Training Program, Western Psychiatric

Institute and Clinic, Pittsburgh, PA

NIMH Research Fellowship T32-MH18399, Biological Psychiatry and Neuroscience, combined with training in Child and Adolescent Psychiatry, Department of Psychiatry, University of California, San Diego

 

M.D.

Intern

 

Resident

 

Research Fellow

Intern

 

Resident

 

Research Fellow

1988-1994

1995-1996

 

1996-1997

 

1998 to date

 

2001-2002

 

2002-2004

 

2004 to date

Medicine

Medicine

 

Psychiatry

 

Psychiatry

 

Adult Psychiatry

 

Adult Psychiatry

 

Research, Child and Adolescent Psychiatry

PROFESSIONAL EXPERIENCE:

1995-1996  Internship at the Psychosomatic Hospital Roseneck / Ludwig-Maximilians-University Munich

1996-1997  Psychiatry Resident at the Psychosomatic Hospital Roseneck / Ludwig-Maximilians-                        University Munich

1994-1997  Doctoral Program (Thesis)

1998 to date      Research Fellow at the Center for Overcoming Problem Eating, Western Psychiatric                         Institute and Clinic, Pittsburgh, PA

2001-2004  Internship and Adult Psychiatry Residency, Western Psychiatric Institute and Clinic, Pittsburgh, PA

2004 to date      NIMH Research Fellowship T32-MH18399, Biological Psychiatry and Neuroscience, Department of Psychiatry, UCSD, combined with clinical training in Child and Adolescent Psychiatry, UCSD Child and Adolescent Psychiatry Training Program, San Diego

HONORS:

1. Christina Barz-Scholarship Award for the promotion of research in the field of eating disorders, July 1997

2. Pilot / Feasibility Grant Award, Obesity and Nutrition Research Center, University of Pittsburgh, PA, January 2000

3. NARSAD Young Investigator Award, March 2001                                 

4. Society of Biological Psychiatry Lilly Travel Fellowship Award, May 2004,

5. Workshop on Clinical Trials Travel Fellowship, American Society of Clinical Psychopharmacology (ASCP), May 2004                                           

6. American Academy of Child and Adolescent Psychiatry, Outstanding Child and Adolescent Psychiatry Resident Award, September, 2004

7. Fellow in the Group for the Advancement of Psychiatry (Period 2005-2007), December 2004

8. Forest Laboratories/West Coast College of Biological Psychiatry Junior Faculty Award, March 2005

 

PUBLICATIONS:

Articles

1.                   Spannagl M, Trauner A, Birg A, Frank G, Hoffmann H, Siebeck M, Lill H. Sensitive detection of the activation state of blood coagulation in porcine DIC models by a new fibrin immunoassay. Blood Coag Fibrinol, 1993, Vol. Nr. 4, 103-106.

2.                   Spannagl M, Frank G, Goedde M, Hoffmann H. The Xanthine derivatives HWA 138 and A 80 attenuate activation of coagulation in porcine endotoxin shock. In: Mueller-Berghaus G, Madlener K, Blombeck M, ten Cate JW (eds.): Pathogenesis, diagnosis and therapy of disseminated intravascular fibrin formation. Amsterdam: Excerpta Medica International Congress Series Nr. 1044, 1993, pp 239-242.

3.                   Hoffmann H, Weis M, Frank G, Birg A, Schoenharting MM, Jochum M. Amelioration of endotoxin-induced acute lung injury in pigs by HWA 138 and A 80 2715: new analogs of Pentoxifylline. Shock, 1995, Vol. Nr. 4, Nr. 3, pp 166-170.

4.                   Cuntz U, Frank G, Fichter MM. Interrelationships between the size of pancreas and the weight of patients with eating disorders. Int J of Eat Disord 27: 297-303, 2000.

5.                   Kaye WH, Frank GK, McConaha C. Altered dopamine activity after recovery from restricting-type anorexia nervosa. Neuropsychopharmacology (1999), Vol 21:503-506.

6.                   Meltzer CC, Cantwell MN, Greer PJ, Ben-Eliezer D, Smith G, Frank G, Kaye WH, Houck PR, Price JC. Does cerebral blood flow decline in healthy aging? A PET study with partial-volume correction. J Nucl Med. 2000;41(11):1842-8.

7.                   Frank GK, Kaye WH. Sertraline in binge eating/purging type anorexia - five case reports. Int J Eat Disorders 29(4):495-498, 2001.

8.                   Kaye, W.H., Frank, G.K., & Klump, K.L. (2000). Psychophysiology of obsessional behaviors in anorexia and bulimia nervosa. In L. Bellodi and F. Brambilla (Eds.), Eating Disorders and Obsessive Compulsive Disorder: An Etiopathogenetic Link? Turin, Italy: Centro Scientifico Editore.

9.                   Frank GK, Kaye WH, Altemus M, Greeno CG. Oxytocin and Vasopressin after recovery from Bulimia Nervosa and binge-eating/purging type Anorexia Nervosa. Biol Psychiatry 2000; 48:315-318.

10.               Kaye WH, Frank GK,  Meltzer CC, Price JC, McConaha C, Crossan PJ, Klump KK,  Bernie J. Devlin BJ. Altered medial orbital frontal serotonin receptor activity after recovery from bulimia nervosa. Am J Psychiatry 158(7):1152-1155, 2001

11.               Frank GK, Kaye WH, Weltzin TE, Perel J, Moss H, McConaha C, Pollice C. Altered response to m-CPP in anorexia nervosa: support for a persistent alteration of serotonin activity after short term weight restoration. Int J Eat Disorders 30(1):57-68, 2001.

12.               Frank GK, Kaye WH, Greer P, Meltzer CC, Price JC. Regional cerebral blood flow after recovery from bulimia nervosa, and possible relations to state anxiety and novelty seeking. Psychiatry Research: Neuroimaging 2000. 100(1):31-39.

13.               Frank GK, Kaye WH, Ladenheim EE, McConaha C. Reduced Gastrin Releasing Peptide in CSF after recovery from Bulimia Nervosa. Appetite 37:871-879, 2001.

14.               Frank GK, Kaye WH, Sahu A, Fernstrom J, McConaha C. Does reduced CSF Galanin contribute to altered taste related  hedonics in anorexia nervosa?  Neuropsychopharmacology 24(6):705-709, 2001

15.               Malina A, Gaskill J, McConaha C, Frank G, LaVia M, Scholar L, Kaye W.  Olanzapine treatment of anorexia nervosa. A retrospective study. Int J Eat Disord. 2003 Mar;33(2):234-7.

16.               Frank GK, Kaye WH, Meltzer CC, Price JC, Greer P, McConaha C, Skovira K. Reduced 5-HT2A receptor binding after recovery from anorexia nervosa. Biol Psychiatry. 2002 Nov 1;52(9):896-906.

17.               Stein D, Kaye WH, Matsunaga H, Orbach I, Har-Even D, Frank G, McConaha CW, Rao R. Eating-related concerns, mood, and personality traits in recovered bulimia nervosa subjects: a replication study. Int J Eat Disord. 2002 Sep;32(2):225-9.

18.               Bailer UF, Frank GK, Henry SE, Price JC, Meltzer CC, Weissfeld L, Mathis C, Drevets WC, Wagner A, Hoge J, Ziolko SK, McConaha CW, Kaye WH. Increased Brain Serotonin 5-HT1A Receptor Binding after Recovery from Anorexia Nervosa Measured by Positron Emission Tomography and [11C]WAY100635. (Accepted for publication Archives of General Psychiatry).

19.               Barbarich N, McConaha C, Gaskill J, LaVia M. Frank GK, Brooks S, Kaye WH, Plotnicov K. An open trial of olanzapine in anorexia nervosa. Int J Eat Disord. 2004 Jan;35(1):10-5.

20.               Frank GK, Kaye WH, Carter CS, Brooks S, May C, Fissel K, Stenger VA. The evaluation of brain activity in response to taste stimuli-a pilot study and method for central taste activation as assessed by event-related fMRI.
J Neurosci Methods. 2003 Dec 30;131(1-2):99-105.

21.               Bailer UF, Price JC, Meltzer CC, Mathis CA, Frank GK, Weissfeld L, et al. Altered 5-HT2A Receptor Activity after Recovery from Bulimia-type Anorexia Nervosa: Relationships to Harm Avoidance and Drive for Thinness. Neuropsychopharmacology. 2004;29(6):1143-55.

22.               Frank GK, Wagner A, Brooks-Achenbach S, McConaha C, Skovira K, Aizenstein H Cameron S. Carter, Walter H. Kaye. Altered Brain Activity in Women Recovered From Bulimic Type Eating Disorders After A Glucose Challenge. (Accepted for publication in International J of Eating Disorders). 23.               Frank GK, Bailer UF, Henry SE, Price JC, Meltzer CC, Weissfeld L, Mathis C, Drevets WC, Wagner A, Hoge J, Ziolko SK, McConaha CW, Kaye WH. Increased dopamine D2/D3 receptor binding after recovery from anorexia nervosa measured by positron emission tomography and [11C]raclopride. (accepted for publication pending minor revisions, Biol Psych) 24.               Bovo V, Bertoldo A, Price JC, Frank GK, Kaye WH, Cobelli C. Examination of a three-tissue compartment model for [11C]WAY-100635: Insight and comparison with a two-tissue compartment model. NEUROIMAGE 22: T65-T66 Suppl. 2, 2004 25.               Lee M, Bailer UF, Frank GK, Henry SE, Meltzer CC, Price JC, Kaye WH. Relationship of a 5-HT transporter functional polymorphism to 5-HT1A receptor binding in healthy women. (Accepted for publication in Molecular Psychiatry)

Book Chapters and Review Articles

1.                   Kaye WH, Klump K, Frank GK, Strober M. Anorexia and Bulimia Nervosa. Annu Rev Med 2000. 51:299-313 (Review)

2.                   Frank GK. Perspectives for Pharmacological Interventions in Eating Disorders. In: Handbook of Medical Psychiatry. Gershon S and Soares J (Editors). Marcel Dekker, New York. 2003. (Book Chapter)

3.                    Frank GK, Bailer UF, Wagner A, Henry S, Kaye WH. Neuroimaging Studies in Eating Disorders. CNS Spectr. 2004;9(7):539-548 (Review).

 

 

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last edited: 12/02/2007